Halfon and Kuo review the history and rationale for the proposed changes for the Diagnostic and Statistical Manual of Mental Disorders, fifth edition, and consider how the proposed changes are likely to create new challenges for parents attempting to organize their children’s care and for pediatricians providing that care and assisting with care coordination.

Flaherty and colleagues conducted a prospective analysis of the Longitudinal Studies of Child Abuse and Neglect data to examine the relationship between previous adverse childhood experiences (ACEs) and somatic concerns and health problems in early adolescence, as well as the role of the timing of adverse exposures.

A cross-sectional, questionnaire distributed to 91 642 children aged 0 to 17 years enrolled in the 2007-2008 National Survey of Children's Health was used by Silverberg et al to study the association between US birthplace and prevalence of childhood allergic disease and to determine the effects of prolonged US residence.

Reviewing the literature from 1950 through 2000, Brosco et al explored the impact of medical interventions in early childhood on the prevalence of later intellectual disability.

In the National Institutes of Health–funded Pediatric HIV/AIDS Cohort Study’s Adolescent Master Protocol, Lipshultz and coauthors used linear regression models to compare echocardiographic measures to determine the cardiac effects of prolonged exposure to highly active antiretroviral therapy on children infected with human immunodeficiency virus (HIV).