Use setStyle() method

           
<?xml version="1.0"?>
<mx:Application xmlns:mx="http://www.adobe.com/2006/mxml">
    <mx:Script>
        
        private function initVBox():void {
            myVBox2.setStyle("paddingTop", 12);
            myVBox2.setStyle("paddingBottom", 12);
        }
      
    </mx:Script>
    <mx:VBox id="myVBox1" borderStyle="solid">
        <mx:Button label="Submit" />
    </mx:VBox>
    <mx:VBox id="myVBox2" borderStyle="solid"
        initialize="initVBox();">
        <mx:Button label="Submit" />
    </mx:VBox>
</mx:Application>

1.	Use setStyle() method, set it inline, or use Cascading Style Sheets (CSS)
2.	Using setStyle to programmatically manipulate a style property
3.	Use setStyle to change font size
4.	Use setStyle to change font style
5.	Cast target to a UIComponent before calling the setStyle() method
6.	Using the setStyle() method to apply graphical skins
7.	Using setStyle() method with a trigger
8.	Use the setStyle() method to apply the custom class to the item renderer.
9.	Use getStyle() with effects defined in MXML
10.	Use getStyle() with behaviors defined in MXML
11.	Set a style property inline, and then reads that property with the getStyle() method

Use setStyle() method : Style Get Set « Style « Flex

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