A translation randomized trial of culturally specific lifestyle intervention for diabetes prevention in India (LT07-115)

Main institution:
Rollins School of Public Health, Emory University (USA)

Other institution:
Madras Diabetes Research Foundation (India)

Principal investigator:
Dr V. Narayan

Other investigators:
Dr M.Hennink; Dr V.Mohan; G.Pradeepa; M.B Weber; P Zhang

Location of the project:
India

Amount allocated:
USD 398,674

Date:
May 1, 2008 - December 31, 2011

Objectives:
People from the Indian subcontinent are more likely to get diabetes even at younger ages. This project describes a randomized trial of culturally specific, community-based lifestyle intervention for the prevention of type 2 diabetes in men and women living in Chennai, India. Lifestyle interventions are programmed to seek to prevent diseases by promoting changes in health behaviors, improved diet, increased physical activity and weight loss. The results of this program will be used to make policy and public health recommendations, which will result in broader diabetes prevention efforts.

Results to date (June 2013):

Presentations:

• 20th World Diabetes Congress, Montreal, Canada, October 2009
• Research Society for the Study of Diabetes in India (RSSDI), Ahmedabad, India, November 2009
• National Chronic Disease meeting, October 2009, New Delhi (India)
• Emory Medical Grand Rounds, March 2010, Atlanta (USA)
• American Diabetes Association Scientific Sessions, June 2010, San Diego (USA)
• Latin American Summit on Diabetes, July 2010, Salvadore (Brazil)
• Diabetes Conference, September 2010, Mexico City (Mexico)
• Consortium of University of Global Health, September 2010, Seattle (USA)
• Emory Global Health Seminar, September 2010, Atlanta (USA)
• Research Society for the Study of diabetes in India, November 2010, India
• International Latin American Associaton of Diabetes, November 2010, Santiago (Chili)
• DFID World Bank workshop, December 2010, Shanghai (China)
• World Diabetes Congress, December 2011, Dubai (UAE)
• World Congress for the prevention of diabetes and its complications, November 2012, Madrid (Spain)
• Research Society for the Study of Diabetes in India, November 2012, Chennai (India)
• Research Society for the Study of Diabetes in India, November 2013, New Delhi (India)
• World Diabetes Congress, December 2013, Melbourne (Australia)

Articles:

• Express Buz, July, 2011 "Experts reccomend D-CLIP for diabetes"
• The Hindu, July 6, 2011 "Modifications in lifestyle show healthy results for diabetics: study"
• Decan Chronicle, July 6,2011 "Exercise keeps diabetes away"
• New Kerala, July 5, 2011 "Number of diabetics in India to touch 85 million by 2030"
• Emory Health News, July 25, 2011 "Exercise, changes in diet alter course for pre-diabetics

Papers:

• Staimez LR, Weber MB, Ranjani H, et al.” Beta cell function in Asian Indians: evidence for marked early declines” Diabetes Care 2013; Online ahead of print April 17, 2013.

• Weber MB, Ranjani H, Meyers GC, Mohan V, Narayan KM. “A model of translational research for diabetes prevention in low and middle–income countries: The Diabetes Community Lifestyle Improvement Program (D–CLIP) trial” Prim Care Diabetes 2012; 6(1): 3-9.

* Project completed in October 2011, results to be announced soon

BRIDGES (Bringing Research in Diabetes to Global Environments and Systems) is a programme initiated by the International Diabetes Federation, and supported by an educational grant from Lilly Diabetes.