Andrea Baccarelli
Department of Environmental Health, Department of Epidemiology
Diseases: Respiratory & Cardiovascular Disease, Childhood Obesity, Fetal-growth Restriction, Cognitive Decline, Hypertension
Research: Investigates the molecular mechanisms and biomarkers that reflect reprogramming of health and disease trajectories in response to environmental exposures.
Barry R. Bloom
Department of Immunology and Infectious Diseases
Diseases: Tuberculosis
Research: Immune response to tuberculosis.
Joseph Brain
Department of Environmental Health
Diseases: Environmental Lung Disease, Respiratory Infection
Research: Responses to inhaled gases, particulates, and microbes.
Barbara Burleigh
Department of Immunology and Infectious Diseases
Diseases: Chagas’ disease
Research: Molecular basis of host cell invasion, signaling and differentiation by the human pathogen, Trypanosoma cruzi.
Flaminia Catteruccia
Department of Immunology and Infectious Diseases
Diseases: Malaria
Research: Reproductive biology of malaria vector, Anopheles gambiae; development of new targets for vector control.
David Christiani
Department of Environmental Health, Department of Epidemiology
Diseases: Cancer, Acute and Chronic Lung Disease, Birth Outcomes and Development, Metabolic Disorder
Research: Studying the impact of exposures to various pollutants on health and the interactions between host factors and environmental exposures in producing acute and chronic diseases.
Immaculata De Vivo
Department of Epidemiology
Diseases: Hormonal Cancers – Endometrial, Breast and Ovarian
Research: Understand mechanisms of carcinogenesis and to establish association with disease for future prevention.
Manoj Duraisingh
Department of Immunology and Infectious Diseases
Diseases: Malaria
Research: Molecular mechanisms underlying the pathogenesis of human malaria.
Myron Essex
Department of Immunology and Infectious Diseases
Diseases: HIV
Research: Virology, immunobiology, and molecular epidemiology of HIV-1 viruses, oriented to the evolution of new viruses, both circulating recombinant forms and variants that emerge by accumulation of mutations.
Robert Farese
Department of Genetics and Complex Diseases
Diseases: Obesity, Diabetes Mellitus, Fatty liver disease, Atherosclerosis
Research: How cells regulate the abundance of lipids, store lipids to buffer fluctuation in their availability and how these processes function in membrane biology and cell physiology.
Sarah Fortune
Department of Immunology and Infectious Diseases
Diseases: Tuberculosis
Research: Secretion and pathogenesis in M. tuberculosis.
Jeffrey Fredberg
Department of Environmental Health
Diseases: Asthma
Research: Identification of the mechanical basis of airway and lung parenchymal function at the levels of organ, tissue, cell, and protein.
Wendy Garrett
Department of Immunology and Infectious Diseases, Department of Genetics and Complex Diseases
Diseases: Inflammatory Bowel Disease, Colon Cancer
Research: Interplay between the innate immune system and intestinal microbial communities.
Tiffany Horng
Department of Genetics and Complex Diseases, Department of Immunology and Infectious Diseases
Diseases: NIrp3 inflammasoome, Macrophage Biology, Chronic Inflammatory diseases, Autoinflammatory diseases
Research: Focus is on the transcriptional mechanisms that regulate inflammatory gene expression.
Gökhan Hotamisligil
Department of Genetics and Complex Diseases, Department of Nutrition
Diseases: Diabetes, Insulin resistance, Obesity, Atherosclerosis
Research: Regulatory pathways which control energy metabolism.
Curtis Huttenhower
Department of Biostatistics
Diseases: Human Microbiome, Computational Biology, Microbial Ecology, Inflammatory Bowel Disease, Autoimmune disorders
Research: Computational methods for systems biology using data mining in large genomic data collections.
Phyllis Kanki
Department of Immunology and Infectious Diseases
Diseases: HIV/AIDS
Research: Explore viral mechanisms for the differences in observed biology between HIV-2 and HIV-1.
Lester Kobzik
Department of Environmental Health
Diseases: Lung Disease, Asthma, Prenatal programming for adult disease, Pneumonia, Influenza
Research: Lung macrophage differentiation and function; flow cytometry applications for respiratory cell biology.
Chih-Hao Lee
Department of Genetics and Complex Diseases, Department of Nutrition
Diseases: Metabolic diseases, Obesity
Research: Nuclear lipid receptors as therapeutic targets of metabolic diseases.
Tun-Hou Lee
Department of Immunology and Infectious Diseases
Diseases: HIV
Research: Virus-specific antigens and their association with disease manifestations, viral replication, and host-virus interactions.
Bernardo Lemos
Department of Environmental Health
Diseases: Pollution, Metals, Epigenetics
Research: Development of a functional and populational understanding of the mapping between genotypes, phenotypes, and environments.
Marc Lipsitch
Department of Epidemiology, Department of Immunology and Infectious Diseases
Diseases: Streptococcus pneumoniae, Antigenic variation, Antimicrobial resistance
Research: Effect of naturally acquired host immunity, vaccine-induced immunity & other public health interventions on population biology of pathogens
Quan Lu
Department of Environmental Health, Department of Genetics and Complex Diseases
Diseases: Asthma, Diabetes, Adrenergic receptor signaling, Gene-environment interaction, Metal toxicants, RNAi screen, Non-coding RNAs
Research: Developing and applying genomewide RNAi tools to study receptor signaling and gene environment interactions.
William Mair
Department of Genetics and Complex Diseases
Diseases: Aging, Cancer, Metabolic Disease, Alzheimer’s Disease
Research: Molecular pathways underpinning the aging process.
Brendan Manning
Department of Genetics and Complex Diseases; Faculty Director, PhD Program in Biological Sciences in Public Health
Diseases: Cancer, Genetic Tumor Syndromes, Type-2 Diabetes, Obesity, Aging
Research: Signaling pathways underlying tumorigenesis and metabolic diseases.
Matthias Marti
Department of Immunology and Infectious Diseases
Diseases: Malaria
Research: Host-pathogen interactions in malaria parasites.
James Mitchell
Department of Genetics and Complex Diseases
Diseases: Surgical stress, Malaria, Cockayne Syndrome
Research: Molecular mechanisms of lifespan extension by nutritional intervention.
Eric Rubin
Department of Immunology and Infectious Diseases
Diseases: Tuberculosis
Research: Virulence factors of mycobacteria; acquisition of virulence determinants of Vibrio cholerae; generalized transposon mutagenesis systems for bacteria.
Frank Sacks
Department of Nutrition
Diseases: Coronary Heart Disease, Hyperlipidemia, Hypertension
Research: Human lipoprotein metabolism, biochemical epidemiology involving lipoproteins and fatty acids and clinical trials in cardiovascular disease.
Stephanie Shore
Department of Environmental Health
Diseases: Asthma, Environmental Pollution, Obesity
Research: Relationship between hormones and inflammatory cytokines produced in adipose tissue and the lungs increased response to asthma triggers.
Joseph Sodroski
Department of Immunology and Infectious Diseases
Diseases: HIV/AIDS
Research: Human immunodeficiency virus envelope glycoproteins; HIV-1 vaccine development.
Vishal Vaidya
Department of Environmental Health
Diseases: Kidney Diseases
Research: Cellular and molecular mechanisms of kidney exposure biology with a special emphasis on biomarkers, biosensors and tissue regeneration.
Tobias Walther
Department of Genetics and Complex Diseases
Diseases: Metabolic Diseases, Neurodegenerative Diseases
Research: How cells regulate the abundance of lipids, store lipids to buffer fluctuation in their availability and how these processes function in membrane biology and cell physiology.
Marianne Wessling-Resnick
Department of Genetics and Complex Diseases, Department of Nutrition
Diseases: Hemochromatosis, Magnanese Neurotixcity, Iron Deficiency, Gene-environment interactions
Research: Regulation of the cellular uptake of transferrin; membrane transport of iron.
Dyann Wirth
Chair, Department of Immunology and Infectious Diseases; Faculty Chair, Harvard Integrated Life Sciences (HILS), Graduate School of Arts and Sciences
Diseases: Malaria
Research: Molecular genetic analysis of gene expression, malaria parasites.
Zhi-Min Yuan
Department of Genetics and Complex Diseases
Diseases: Aging, Diabetes, Cancer
Research: Elucidation of signaling mechanisms that regulate cellular stress responses; examining how stress signals affect cell behaviors in the context of cancer.