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Apr 1, 2022 - Java
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next-generation-sequencing
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Java utilities for Bioinformatics
A curated list of resources for learning bioinformatics.
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Feb 23, 2022
NGMLR is a long-read mapper designed to align PacBio or Oxford Nanopore (standard and ultra-long) to a reference genome with a focus on reads that span structural variations
docker
mapper
next-generation-sequencing
alignment
long-read
pacbio
bioconda
oxford-nanopore
structural-variations
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Aug 16, 2021 - C++
Rapid large-scale prokaryote pan genome analysis
bioinformatics
research
genomics
pathogen
sequencing
next-generation-sequencing
bioinformatics-pipeline
global-health
infectious-diseases
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Sep 26, 2020 - Perl
Fast taxonomic classification of metagenomic sequencing reads using a protein reference database
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Mar 25, 2022 - C
Finds SNP sites from a multi-FASTA alignment file
bioinformatics
research
genomics
pathogen
sequencing
next-generation-sequencing
bioinformatics-pipeline
global-health
infectious-diseases
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Dec 16, 2020 - C
Artemis is a free genome viewer and annotation tool that allows visualization of sequence features and the results of analyses within the context of the sequence, and its six-frame translation
bioinformatics
research
genomics
pathogen
sequencing
next-generation-sequencing
bioinformatics-pipeline
global-health
infectious-diseases
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Mar 15, 2022 - Java
Analysis pipeline to detect germline or somatic variants (pre-processing, variant calling and annotation) from WGS / targeted sequencing
workflow
bioinformatics
pipeline
annotation
genomics
nextflow
cancer
reproducible-research
containers
conda
next-generation-sequencing
variant-calling
somatic
germline
whole-exome-sequencing
whole-genome-sequencing
pre-processing
nf-core
gatk4
target-panels
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Mar 31, 2022 - Nextflow
A tool to circularize genome assemblies
bioinformatics
research
genomics
pathogen
sequencing
next-generation-sequencing
bioinformatics-pipeline
global-health
infectious-diseases
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Nov 2, 2021 - Python
Detect germline or somatic variants from normal or tumour/normal whole-genome or targeted sequencing
docker
workflow
bioinformatics
pipeline
genomics
nextflow
cancer
somatic-variants
reproducible-research
containers
next-generation-sequencing
singularity
badge
reproducible-science
travis-link
somatic
germline
scilifelab
gitter-badge
germline-variants
gitter-link
scilifelab-link
nextflow-link
nbis-link
ngi-link
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Jan 27, 2020 - Nextflow
An efficient FASTQ manipulation suite
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Jan 27, 2020 - C
ammaraziz
commented
Feb 21, 2022
When running nextclade dataset list the output is ~200 lines of information. The number of datasets may grow in the future and so would the output. It would be super handy to have a flag that reduces the verbosity of the list output. Possible truncated output might be:
Dataset
-------
Friendly name : SARS-CoV-2
Safe name : sars-cov-2
Default reference : MN90894
t:feat
Type: request of a new feature, functionality, enchancement
good first issue
Good for newcomers
help wanted
Extra attention is needed
Antimicrobial Resistance Identification By Assembly
bioinformatics
research
genomics
pathogen
sequencing
next-generation-sequencing
bioinformatics-pipeline
global-health
infectious-diseases
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Jan 31, 2022 - Python
Rare variant test software for next generation sequencing data
c-plus-plus
gwas
kernel
genetics
ngs
next-generation-sequencing
variants
meta-analysis
genotype
umich
skat
association-analysis
rare-variant
vcf-files
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Jan 26, 2022 - C++
Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins
bioinformatics
research
genomics
pathogen
sequencing
next-generation-sequencing
bioinformatics-pipeline
global-health
infectious-diseases
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Mar 2, 2022 - Python
Dockerised Next Generation Sequencing Pipeline (QC, Align, Calling, Annotation)
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Jul 10, 2017 - Shell
NextGenMap is a flexible highly sensitive short read mapping tool that handles much higher mismatch rates than comparable algorithms while still outperforming them in terms of runtime. This allows analysing large scale datasets even with increased SNP rates or higher error rates (e.g. caused by specialized experimental protocols) and avoids biases caused by highly variable regions in the genome.
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May 15, 2019 - C++
Get assembly statistics from FASTA and FASTQ files
bioinformatics
research
genomics
pathogen
sequencing
next-generation-sequencing
global-health
infectious-diseases
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Nov 2, 2021 - C++
Program for estimating πN/πS, dN/dS, and other diversity measures from next-generation sequencing data
evolution
perl
next-generation-sequencing
vcf
population-genetics
dnds-estimation
molecular-evolution
nucleotide
fasta-sequences
vcf-files
diversity-measurement
sequence-analysis
dnds
natural-selection
snp-report
nucleotide-diversity
evolutionary-parameters
substitution-rate
nei-gojobori
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Jul 5, 2021 - Perl
Infectious Disease Sequencing Platform
science
bioinformatics
research
genomics
biology
sequencing
computational-biology
next-generation-sequencing
bioinformatics-pipeline
global-health
virology
infectious-diseases
metagenomic
czid
chan-zuckerberg-id
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Apr 1, 2022 - JavaScript
DeepMicrobes: taxonomic classification for metagenomics with deep learning
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Feb 19, 2020 - Python
Microsatellite Instability (MSI) detection using high-throughput sequencing data.
next-generation-sequencing
hypermutation
msisensor
microsatellite-instability
dna-missmatch-repair-system
tumor-only-support
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Sep 14, 2021 - C++
bioinformatics
research
genomics
pathogen
sequencing
next-generation-sequencing
global-health
infectious-diseases
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Jan 6, 2021 - Jupyter Notebook
Python3 scripts to manipulate FASTA and FASTQ files
bioinformatics
research
genomics
pathogen
sequencing
next-generation-sequencing
global-health
infectious-diseases
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Nov 2, 2021 - Python
Analysis Workflow for Assay for Transposase-Accessible Chromatin using sequencing (ATAC-Seq)
sequencing
next-generation-sequencing
atac-seq
chromatin
nucleosome-positioning
peak-detection
atac-seq-pipeline
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Oct 28, 2021 - Shell
Improve the quality of a denovo assembly by scaffolding and gap filling
bioinformatics
research
genomics
pathogen
sequencing
next-generation-sequencing
bioinformatics-pipeline
global-health
infectious-diseases
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Jan 4, 2021 - Perl
de novo virus assembler of Illumina paired reads
bioinformatics
research
genomics
pathogen
sequencing
next-generation-sequencing
bioinformatics-pipeline
global-health
infectious-diseases
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May 17, 2021 - Python
A high throughput sequence read toolset using a streaming approach facilitated by Linux pipes
streaming
bioinformatics
genomics
next-generation-sequencing
sequence-analysis
bioinformatics-tool
linux-pipes
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Mar 21, 2022 - C++
DNAscan is a fast and efficient bioinformatics pipeline that allows for the analysis of DNA Next Generation sequencing data, requiring very little computational effort and memory usage.
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Feb 9, 2022 - HTML
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When working with very large SAM files it is often convenient to remove sequence and quality information to reduce storage and improve I/O.
Following from this it would be convenient to have a
stripSeqQualfunction that replaces the two fields with*.